摘要
目的探讨高血糖高渗状态(HHS)患者的心肌酶谱的变化病因及相关因素。方法将46例糖尿病患者分为两组:HHS组24例高血糖高渗状态患者;T2DM组22例无急性并发症T2DM患者,有效血浆渗透压(POP)均低于310mmol/L。分别监测各组的心肌酶,分析HHS组患者的心肌酶与血糖、血Na+、血UA、POP的关系。结果 (1)HHS组心肌酶各指标均明显高于T2DM组(P<0.05,P<0.01)。(2)心肌酶各指标均与POP呈正相关,肌酸激酶(CK)并与血UA呈正相关。结论 (1)HHS易于诱发横纹肌溶解症,心肌酶谱宜作为常规检查项目。(2)HHS时心肌酶增高主要与POP升高程度有关。
Objective To explore the causes and related factors of the myocardial enzyme changes in the patients with hyperglycemic hyperosmolar status （HHS）. Methods Forty-six cases of diabetes mellitus were divided into two groups. 24 with HHS （HHS group） and 22 without HHS （T2DM）. The effective plasma osmolar pressure （POP） was more than 320 mmol/L in HHS group, and less than 310 in T2DM group. The myocardial enzymes were detected and their relations with blood glucose, blood Na＋ , serum uric acid （UA）, and POP were analyzed. Results （1）The myocardial enzyme indices were significantly higher in the HHS group than in T2DM group （P〈0. 05, P〈0. 01）. （2）The myocardial enzyme indices were positively related with POP, and ereatine kinase （CK） was positively related with serum UA. Conclusion （1） Rhabdomyolysis might be induced by HHS. The myocardial enzymes, especial CK, should be monitored routinely at the beginning of HHS. （2） In HHS, the increase in myocardial enzyme is mainly related with the increased degree of POP.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2012年第7期507-510,共4页
Chinese Journal of Diabetes
关键词
糖尿病并发症
心肌酶谱
横纹肌溶解
Diabetic complications
Myocardial enzyme
Rhabdomyolysis
