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脱钙骨基质的骨修复功能及其在口腔临床医学中的应用前景 被引量:1

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摘要 脱钙骨基质(demineralized bone matrix,DBM)是同种异体或异种骨经过脱钙、脱脂、去蛋白处理得到的产物,主要成分包括胶原和骨形态发生蛋白(bone morphogenetic proteins,BMPs),具有良好的生物相容性和满意的三维空间结构,并且能够诱导未分化的间充质细胞分化为成骨和成软骨细胞,在骨、软骨缺损修复中具有重要作用。目前,应用DBM进行骨缺损的修复治疗显示了良好的临床效果,本文针对DBM在骨缺损修复中的作用机制及其在口腔颌面部的应用做一综述,并展望DBM在牙体牙髓修复中的应用。
出处 《口腔生物医学》 2012年第2期94-97,共4页 Oral Biomedicine
基金 江苏高校优势学科建设工程资助项目
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