摘要
目的探讨颅脑损伤并发抗利尿激素分泌异常综合征的机制、临床特征及治疗转归。方法回顾分析我科近9年收治的9例颅脑损伤合并抗利尿激素分泌异常综合征患者的临床资料。结果 9例患者均具有低钠血症、低渗血症及高尿钠症。8例治愈,1例死亡。结论抗利尿激素分泌异常综合征是由于下丘脑直接或间接受损所致,临床特征为难以纠正的低钠和低血浆渗透压;早期诊治能降低病残率及死亡率;治疗的关键是严格控制摄入水量,适量补钠。
Objective To analyze the cause,the clinical feature and treatment of syndrome of inappropriate antidiuretic hormone with brain injury.Methods The clinical data of 9 patients of brain injury with syndrome of inappropriate antidiuretic hormone treated in our department in the past 9 years were retrospectively analyzed.Results The 9 patients all had hyponatremia,low plasma osmotic pressure and high urine sodium.Eight of the patients were cured and one died.Conclusion Syndrome of inappropriate antidiuretic hormone is caused by injury to the hypothalamus directly or indirectly.The clinical features are mainly irreformable hyponatremia and hyposmolality.Early diagnosis and treatment can reduce the morbidity and mortality.The crux of therapy is that the patients should be controlled with vigorous water restriction and be given sodium properly.
出处
《海南医学》
CAS
2012年第13期56-57,共2页
Hainan Medical Journal
关键词
抗利尿激素分泌异常综合征
颅脑损伤
低钠血症
Syndrome of inappropriate antidiuretic hormone； Brain injury； Hyponatremia
