摘要
目的 探讨硬膜外镇痛对产妇血清催乳素 (prolactin ,PRL)的影响。方法 选择 5 0例产妇随机分为镇痛组(E组 )和对照组 (C组 )。E组在宫口开至 3～ 4cm时开始硬膜外镇痛 ,镇痛药为 0 12 5 %布比卡因 (每ml含 2 μg芬太尼 ) ,C组按产科常规处理。分别在产前、产后 2h及产后 2 4h抽取母亲静脉血采用放免法测定血清PRL ,并观察镇痛效果及哺乳情况。结果 硬膜外镇痛效果良好 ,两组产妇血清PRL及泌乳始动时间差异无显著性。结论 硬膜外低浓度布比卡因复合芬太尼行无痛分娩镇痛效果良好 。
Objective To study the influence of epidural analgesia on serum prolactin (PRL) concentration and the first time of lactation in parturient.Methods Fifty labor women were divided into two groups. Twenty-five parturients were selected as epidural analgesia group (E group) and other were as nature delivery group (C group). In E group 0 125% bupivacaine with fentanyl were given into epidural space while utero-cervical was opened to 3～4 cm. The serum PRL concentration was tested before and after 2 h, 24 h hours of labor period with radioimmunoassay. Analgesia effect and lactation were observed as well.Results The excellent pain relief were observed in epidural analgesia group. There were no significant difference of serum PRL concentrations and the initial time of lactation between two groups.Conclusion Low concentration bupivacaine and fentanyl in epidural space for labor pain relief can induce excellent analgesia, and no influence on serum PRL concentration and the initial time of lactation.
出处
《广东医学》
CAS
CSCD
2000年第5期355-356,共2页
Guangdong Medical Journal
基金
广东省卫生厅立项
关键词
镇痛
分娩
催乳素
硬膜外镇痛
Analgesia, epidural\ Labor delivery\ Prolaction
