摘要
目的:观察白蛋白结合型紫杉醇(Abraxane)联合替吉奥(S-1)一线治疗晚期胃癌的疗效和安全性。方法:Abraxane125mg/m^2,在化疗的第1和第8天,S-1每天60mg/m^2,分2次,从化疗的第1到第14天;3周为一个周期,至少完成2个周期。结果:19例患者PR11例,SD4例,PD4例,毒副反应可以耐受。结论:白蛋白结合型紫杉醇作为一种新型紫杉类化疗药联合替吉奥一线治疗晚期胃癌具有广阔研究前景。
To observe the effect and security of advanced gastric cancer treaded in line by Abraxane combined with S-1. Methods： The usage of Abraxane 125 mg/㎡, D1 and D8, the usage of S-1 60mg/㎡ Bid P. O. D1-14, after three weeks repeated, at least completed 2 cyclical chemotherapies. Results： The cases of PR, SD and PD in 19 patients were 11,4 and 4 with mild loxicity. Conclusion： Advanced gastric cancer treated in line by Abraxane combined with S-1 will show vast foreground of treatment.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2012年第13期936-938,共3页
Chinese Journal of Clinical Oncology
