摘要
目的探讨冠状动脉粥样硬化性心脏病患者血清超敏C反应蛋白(hs-CRP)水平与冠状动脉病变严重程度的相关性。方法对162例经冠脉造影确诊为冠心病的患者检测hs-CRP,并采用改良的Gensini评分对冠状动脉血管病变程度进行分析,采用Spearman相关性分析分析冠状动脉病变与hs-CRP。结果 Spearman相关性分析显示:hs-CRP与Gensini评分之间差异有统计学意义(r=0.76,P<0.01)。结论血清中hs-CRP水平与冠状动脉病变呈正相关,其浓度随着冠状动脉病变程度的增加而升高,血清hs-CRP水平可作为冠心病患者的冠状动脉病变程度的重要参考指标之一。
Objective To explore the relationship between serum high-sensitivity C-reactive protein(hs-CRP) and coronary atherosclerosis.Method Detecting the hs-CRP of 162 coronary heart disease patients who final diagnosis by coronary arteriongraphy.Using modified Gensini score to analyze the vascular lesion degree.Spearman analysis was used for evaluate the correlation between the coronary artery disease and hs-CRP.Results Spearman associativity showed that,there were statistical significance between Gensini score and hs-CRP(r=0.76,P〈0.01).Conclusions Serum hs-CRP level was positively associated with coronary stenosis degree,as the concentration level rised,the disease was severity.Hs-CRP was one of the indicators for assessing coronary stenosis degree.
出处
《医学动物防制》
2012年第6期705-707,共3页
Journal of Medical Pest Control
关键词
超敏C反应蛋白
冠状动脉粥样硬化
冠状动脉造影术
High-sensitivity C-reactive protein
Coronary atherosclerosis
coronary arteriography