期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

γδT细胞与疾病的关系 被引量：1

γ δT cell is related to diseases
暂未订购
导出
摘要 γδT细胞已是当今细胞治疗研究的热点,活化的γδT细胞具有较强的杀伤活性,具有抗感染、抗肿瘤作用;γδT细胞还可以维持免疫耐受,调节免疫应答,其异常可导致自身免疫性疾病的发生,本文就γδT细胞在这几方面的作用作一综述。 γδT cells have been a research hotspot in cell therapy nowadays. The activated γδT cells with strong cy- totoxic activity have anti - infection and anti - tumor effects.γδTcells can also maintain immune tolerance and regu- late immune response. Its abnormalities can lead to autoimmune diseases. In this paper, γδT cells in the role of these areas are reviewed.
作者 田爱 焦琳 王熙才
机构地区 昆明医科大学第三附属医院肿瘤研究所
出处 《现代肿瘤医学》 CAS 2012年第7期1472-1474,共3页 Journal of Modern Oncology
基金 国家自然科学基金资助项目(编号:81060177) 云南省卫生厅专项基金资助项目(编号:2009NS035)
关键词 ΓΔT细胞 感染性疾病 自身免疫性疾病 肿瘤 γδT cells infectious diseases autoimmune diseases tumors
分类号 R730.231 [医药卫生—肿瘤]
  • 相关文献

参考文献19

  • 1Brenner MB, McLean J, Dialynas DP, et al. Identification of a putative second T - cell receptor[ J ]. Nature, 1986,322 ( 6075 ) : 145 - 149.
  • 2Tfiebel F, Hercend T. Subpopulafions of human peripheral T lymphocytes [J]. Immunol Today, 1989,10 : 186 - 189.
  • 3Hayday AC. [gamma] [ delta] cells: a right time and a right place for a conserved third way of protection [ J ]. Annu Rev Immunol, 2000,18:975 - 1026.
  • 4Martini F, Urso R, Gioia C, et ah gammadeha T - cell anergy in human immunodeficiency virus - infected persons with opportunistic infections and recovery after highly active antiretroviral therapy [J]. Immunology, 2000,100 (4) :481 - 486.
  • 5Kistowska M, Rossy E, Sansano S, et al. Dysregulation of the host mevalonate pathway during early bacterial infection activates human TCR gamma delta cells [ J ]. Eur J Immunol, 2008,38 ( 8 ) :2200 - 2209.
  • 6De Rosa SC, Andrus JP, Peffetto SP, et al. Ontogeny of gamma delta T cells in humans[ J ]. J Immunol, 2004,172 ( 3 ) : 1637 - 1645.
  • 7孙陆果.γδT细胞及其在免疫耐受中的生物学意义[J].国外医学（免疫学分册）,2000,23(2):77-80. 被引量：4
  • 8Caccamo N, Meraviglia S, Ferlazzo V, et al. Differential require- ments for antigen or homeostatic cytokines for proliferation and differentiation of humanVgamma9Vdeha2 naive, memory and effector T cell subsets[J]. Eur J Immunol, 2005,35(6) :1764 - 1772.
  • 9何维.γδT细胞的抗原识别机制[J].中国免疫学杂志,1999,15(10):433-435. 被引量：23
  • 10Martini F, Urso R, Gioia C, et al. Gammadeha T - cell anergy in human immunodeficiency vires - infected persons with opportunistic infections and recovery after highly active antiretroviral therapy [ J ]. Immunology, 2000,100 ( 4 ) :481 - 486.

二级参考文献10

  • 1PenningerJMetal. Nature . 1995
  • 2WeintraubBCetal. Immunologic Research . 1995
  • 3SzczepanikM. FoliaMedCracov . 1998
  • 4BornWetal. Advances in Immunology . 1999
  • 5BoullierSetal. European Journal of Immunology . 1990
  • 6ZocchiMRetal. European Journal of Immunology . 1990
  • 7WildnerGetal. European Journal of Immunology . 1996
  • 8BarrettTAetal. The Journal of Experimental Medicine . 1992
  • 9CatalfanomMetal. JImmunol . 1996
  • 10LiWenetal. Immunologic Research . 1997

共引文献25

同被引文献4

引证文献1

二级引证文献2

现代肿瘤医学
2012年 第7期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部