摘要
目的比较不同剂型的活血化瘀中药治疗冠状动脉粥样硬化性心脏病不稳定性心绞痛的疗效。方法选择冠状动脉粥样硬化性心脏病不稳定性心绞痛心血瘀阻证的患者150例,采用随机数字表法随机分为A组(西药治疗组)、B组(西药加丹红注射液治疗组)、C组(西药加血府逐瘀汤口服治疗组)3组各50例。A组常规给予西药治疗,B组在A组治疗的基础上加用丹红注射液静脉滴注,C组在A组治疗的基础上加用血府逐瘀汤煎汤口服治疗。结果 B、C组分别和A组相比较,在缓解不稳定性心绞痛症状、中医证候的总疗效、24h动态心电图各项指标的改善、硝酸甘油片的停减、升高高密度脂蛋白胆固醇及降低低密度脂蛋白胆固醇等方面明显优于A组(P<0.05);B组和C组在上述诸方面比较差异无统计学意义。结论中西药结合治疗心血瘀阻型不稳定性心绞痛比单独运用西药治疗效果好,而不同剂型活血化瘀中药治疗心血瘀阻型不稳定性心绞痛疗效无明显差别。
Objective To compare the efficacy of different formulations of traditional Chinese medicine in treatment of coronary atherosclerotic heart disease unstable angina. Methods One hundred and fifty cases selected of coronary atherosclerotic heart disease unstable angina of blood stasis syndrome were randomly divided into three groups using a ran- dom number table, group A （Western medicine treatment group）, group B （Danhong Injection plused Western medicine treatment group） and group C （Western medicine combined with Xuefu Zhuyu Decoction treatment group）, 50 cases in each group. Group A was treated with Western medicine routinely, on base of group A, group B was treated with Danhong injec- tion for intravenous injection and group C was treated with Xuefu Zhuyu Decoction oral. Results Group B and C were bet- ter than the group A in the relief of unstable angina, the total curative effect of traditional Chinese medicine syndrome, 24 hours dynamic electrocardiographic indexes improvement, increase high-density lipoprotein cholesterol and decrease low- density lipoprotein cholesterol, ect （P 〈 0.05）, while there were no obvious difference between group B and C. Conclusion Effect of combination of traditional Chinese and Western medicine treatment on unstable angina of blood stasis syndrome is better than Western medicine alone, and there is medicine in treatment of blood stasis type of unstable no difference between different formulations of traditional Chinese angina.
出处
《中国当代医药》
2012年第18期11-13,15,共4页
China Modern Medicine
