摘要
目的 :考察不同醋量对商陆毒性及药效的影响。方法 :采用急性毒性实验 (测LD50 ) ,祛痰实验 (酚红排泌法 )及利尿实验 (滤纸法 )。结果 :商陆醋制后毒性明显降低 ,利尿作用有所缓和 ;生品和 30 %醋煮品祛痰效果较好 ,而 5 0 % ,10 0 %醋量醋煮制商陆较生品差。结论 :商陆以 30 %醋煮制为佳。
Objective:To investigate the effects of different vinegar volume on toxicity and pharmacodynamics of Radix Phytolaccae. Mothods: Using the acute toxicity test (determining LD 50 ), removing the phlegm test cphenolsulfon phthalein excretion test) and diuresis test (filter paper method). Results:The toxicity of Radix Phytolaccae prepared with vinegar decreased obviously, but its diurtic action was somewhat softened. the crude sample and 30% vinegar boiled sample showed a good phlegm removing action, but 50% or 100% vinegar boiled sample was worse than the crude sample. Conclusions: Radix Phytolaccae processed with 30% vinegar is the best.
出处
《中成药》
CAS
CSCD
2000年第4期273-274,共2页
Chinese Traditional Patent Medicine
关键词
商陆
炮制
毒性
药效
醋煮
醋量
Radix Phytolaccae
processing
pharmacological test
