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酮咯酸氨丁三醇超前镇痛对四肢骨科术后镇痛的疗效观察 被引量:4

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摘要 目的评价酮咯酸氨丁三醇超前镇痛对四肢骨科手术的镇痛效果。方法选择骨科四肢手术90例,随机分为A、B、C 3组。A组于手术开始前静注酮咯酸氨丁三醇30mg,B组于术毕缝皮时静注酮咯酸氨丁三醇30mg,C组术前静注等量生理盐水。3组患者术后均行静脉自控镇痛,观察患者术后4、8、12、24、48h内的疼痛评分,术毕至术后4h,术后4h至24h患者PCIA泵按压次数及术后24h芬太尼用量,观察患者嗜睡、头晕、恶心、呕吐等不良反应。结果术后VAS评分,T1~T3时,A组显著低于B组、C组,T1~T2时B组显著低于C组(P<0.05);术毕~术后4h、术后4h^24h PCIA按压次数、术后24h芬太尼用量A、B组均显著低于C组(P<0.05);术毕~术后4h A组PCIA泵按压次数显著少于B组(P<0.05)。结论酮咯酸氨丁三醇超前镇痛配合PCIA用于四肢骨科手术,镇痛效果确切,显著减少阿片类药物用量和不良反应,值得临床推广应用。
出处 《海峡药学》 2012年第6期168-169,共2页 Strait Pharmaceutical Journal
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参考文献3

  • 1林焱斌,李仁斌,张怡元,肖莉莉,李平,宋卫,熊国胜.全膝关节置换术围手术期塞来昔布镇痛疗效评估[J].国际骨科学杂志,2009,30(1):61-63. 被引量:21
  • 2KissinT. preemptive analgesia[J]. Anesthesiology, 2000, 93 ( 4 ): 1138.
  • 3Alsarra IA, Alanazi FK, Mahmus GM, et al. Clinical evaluation of novel bulloadhesive film containing Ketorolac in dental and post-oral sugery pain mangement [J]. pharmazie, 2007, 62 (10) : 773.

二级参考文献7

  • 1Buvanendran A, Kroin JS, Tuman KJ, et al. Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial. JAMA, 2003; 290(18):2411-2418
  • 2Meunier A, Lisander B, Good L.Effects of celecoxib on blood loss,pain, and recovery of function after total knee replacement: a randomized placebo-controlled trial. Acta Orthop, 2007,78(5) :661-667
  • 3Sugano K. Current issues of NSAIDinduced gastrointestinal ulcer in Japan. Nippon Rinsho, 2007;65(10):1754-1758
  • 4Valat JP, Deray G, Heloire F, et al. Are there any differences in the cardiovascular tolerance between classical NSAIDs and coxibs? Presse Med, 2006; 35(Suppl 1 ) :25-34
  • 5Feng Y, Ju H, Yang B, et al. Effects of a selective cyclooxygenase-2 inhibitor on postoperative inflammatory reaction and pain after total knee replacement. J Pain, 2008; 9(1):45-52
  • 6Stiller CO, Lundblad H, Weidenhidm L, et al. The addition of tramadol to morphine via patient-controlled analgesia does not lead to better post-operative pain relief after total knee arthroplasty. Acta Anaesthesiol Stand, 2007; 51(3): 322-330
  • 7Hadi MA, Kamaruljan HS, Saedah A, et al. A comparative study of intravenous patient-controlled analgesia morphine and tramadol in patients undergoing major operation. Med J Malaysia, 2006; 61(5):570-576

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