摘要
目的:对中医常用滋阴补阳方药进行筛选。方法:以ICR纯种小鼠的骨髓细胞为实验材料,用公认的诱变剂环磷酰胺(CPP)诱发的姐妹染色单体互换(SCE)作为指标,研究六味地黄汤、金匮肾气丸、理中汤及桂枝甘草汤对环磷酰胺诱导的SCE的影响。结果:4种方药对SCE均具明显的抑制作用。
Objective:To study the inhibition of Liuweidihuang Decoction, Jinguishengi Pills, Lizhong Decoction and Guizhigancao Decoction on Sister Chromatid Exchanges (SCE) induced by CPP. Methods:The bone marrow cell of pure ICR species of mouse was used as an experimental material and the SCE induced by CPP was used as an index. Results:Four kinds of prescription showed the inhibition on SCE induced by CPP. Conclusion:4 kinds of prescription have a potential prevention ation of tumor.
出处
《中成药》
CAS
CSCD
2000年第3期212-214,共3页
Chinese Traditional Patent Medicine
基金
国家中医药管理局课题!(95YC0 1 2 )
关键词
中医药疗法
环磷酰胺
SCE
小鼠
Liuweidihuang Decoction
Jinguishengi Pills
lizhong decoction
guizhigancao decoction
sister chromatid exchanges (SCE)
Antimutation
