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CDFI定量分析对绝经后子宫内膜增厚的诊断价值 被引量:6

CDFI Blood Flow Analysis in Diagnosis of Postmenopausal Endometrial Thickening
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摘要 目的:应用彩色多普勒超声(CDFI)观察与分析绝经后增厚子宫内膜区动脉血流参数变化与内膜病变的相关性。方法:2008年1月~2012年1月158例绝经后子宫内膜增厚并最终获得病理的患者纳入研究,完成经阴道CDFI检查,测定增厚内膜区动脉血流,分析能量图与收缩期峰值流速(PSV)、舒张末血流最低参数(EDV)和阻力指数(RI)。结果:子宫内膜癌36例,内膜区见多条异常增粗的血管,血流信号增多紊乱,CDFI显示PSV(28±5.1)cm/s,与良性病变(24.6±3.0cm/s)无明显差异;EDV为(16±3.8)cm/s,明显高于良性病变(7.3±2.5cm/s,P<0.05);血流阻力指数(RI<0.43)则明显低于良性病变(RI>0.5)。子宫内膜良性病变122例,其中31例子宫内膜息肉内膜区单根血管延伸至瘤体,CDFI显示低速高阻血流(RI>0.56);35例子宫黏膜下肌瘤内膜区显示环状血流信号,CDFI显示低速高阻血流(RI>0.5);14例子宫内膜增生反应显示内膜区血流信号呈细条状,CDFI显示低速高阻血流(RI>0.68);21例子宫内膜增生反应无血流信号。结论:均匀增厚的内膜内高阻血流的存在是诊断内膜良性病变的关键,而异常增厚内膜内舒张期增高低阻血流的存在是恶性病变的一项重要指标。通过子宫内膜血流的CDFI检测可以帮助鉴别子宫内膜病变的良、恶性。 Purpose:To observe the application of color Doppler imaging(CDFI) in diagnosis of postmenopausal endometrial thickening,and to evaluate the correlation between the blood flow parameters change and the pathology changes of the intimal lesion.Methods: From January 2008 to January 2012,158 cases of postmenopausal endometrial thickening patients with pathology diagnosis were included in the study.Transvaginal CDFI examination was used to evaluate the arterial blood flow of the thickened intimal area.The energy diagram and contraction of peak velocity(PSV),the lowest parameters diastolic of end velocity(EDV) and resistance index(RI) were analyzed.Results: Of all the cases,36 cases were endometrial cancers,abnormal thickening of the blood vessels,increase of blood flow signals disorders were shown in the endometrial areas;the PSV was 28 ± 5.1cm / s on CDFI,and was with no significant statistical difference between them and that of benign lesions(24.6 ± 3.0cm / s);the EDV was 16 ± 3.8cm / s,that was significantly higher than that of benign lesions(7.3 ± 2.5cm / s,P <0.05);flow resistance index(RI <0.43) was significantly lower than that of benign lesions(RI> 0.5).Of 122 cases of endometrial benign lesions,31 cases were endometrial polyps,the features of them included single vascular extension from endometrial area to the tumor,low-speed high resistance blood flow(RI> 0.56) on CDFI;35 cases were uterine submucosal fibroids,the features inclued circumferential blood flow signals,and low-speed high-impedance blood flow(RI> 0.5) on CDFI;14 cases were endometrial hyperplasia reaction,the features included thin strips blood flow signal in intimal areas,and low-speed high-impedance blood flow(RI> 0.68) on CDFI;21 cases were uterine intimal hyperplasia reaction,no blood flow was shown in them.Conclusion: The high resistance blood flow in the presence of a uniform thickening of the intima is the key to the diagnosis of benign endometrial lesions;abnormal thickening of the intima combined with the increase of diastolic low resistance blood flow is an important indicator of the malignant lesions.By CDFI,detection of endometrial blood flow can help the identification of endometrial lesions,and to differentiate benign lesions from malignant.
出处 《中国医学计算机成像杂志》 CSCD 北大核心 2012年第3期259-261,共3页 Chinese Computed Medical Imaging
基金 上海市卫生局局级科研课题资助项目(No:2010-64)~~
关键词 绝经后 子宫内膜增厚 彩色多普勒超声 Postmenopausal Endometrial thickening Color Doppler ultrasound
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二级参考文献2

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同被引文献45

  • 1张丹,李燕东,马彦,张建生,孟焱,翟林.子宫内膜增生过长彩色多普勒超声检查及病理分析[J].中华医学超声杂志(电子版),2007,4(6):368-370. 被引量:18
  • 2朱迎,张丹.子宫内膜癌的超声诊断现状[J].中华临床医师杂志(电子版),2012,6(16):4811-4813. 被引量:10
  • 3葛玲,傅庆诏,刘韶平,陶国伟,展新凤,马喆,车艳辞.经阴道三维超声子宫内膜容积测量在子宫内膜癌诊断中的价值[J].中国超声医学杂志,2005,21(1):48-51. 被引量:14
  • 4Buchanan EM,Weinstein LC,HiUson C.Endometrial cancer[J]. Am Fam physician,2009,80(10):1075-1080.
  • 5Mansour GM,El,Laraie[K E]1-Kady MA,el al.Endometfial volume as predictor of malignancy in women with postmenopausal bleeding[J].Int J Gynaeeol Obstet.2007,99(3):206-210.
  • 6Odeh M,Vainerovsky I,Grinin V,et al.Three-dimensional endometrial volume and 3-dimensional power Doppler analysis in predicting endometrial carcinoma and hyperplasia[J].Gynecol Oncol,2007,106(2):348-353.
  • 7Buchanan EM, Weinstein LC, Hillson C. Endometrial cancer[ J ]. Am Faro Physician, 2009,80(10) : 1075 - 1080.
  • 8Mansour GM, E1 - Lamie IK, E1 - Kady MA, el al. Endometrial vol- ume as predictor of malignancy in women with postmenopausal bleeding [ J ]. Int J Gynaecol Obstet, 2007,99 ( 3 ) : 206 - 210.
  • 9Odeh M, et al. Three - dimensional endometrial volume and 3 - di- mensional power Doppler analysis in predicting endometrial carcino- ma and hyperplasia [ J ]. Gynecol Oncol,2007,106 ( 2 ) : 348.
  • 10Ozbilen O, Sakarya DK, Bezircioglu I, et al. Comparison of myometrial invasion and tumor free distance from uterine serosa irl endometrial cancer [J]. Asian Pac J Cancer Prey, 2015, 16 (2): 519-522.

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