摘要
目的:观察复方仙灵脾冲剂对慢性乙型肝炎患者血清sIL-2R、外周血T淋巴细胞中CD_4/CD_8及eAg的影响。方法:血清sIL-2R检测采用双抗体夹心酶联免疫法;外周血T淋巴细胞亚群检测采用免疫荧光法;HBeAg检测采用ELISA法。结果:复方仙灵脾冲剂可使血清sIL-2R明显下降,与对照组相比差异有显著性(P<0.05),可改善T细胞亚群,使CD_4/CD_8值上升,与对照组相比差异有非常显著性(P<0.01),并且有一定的抗病毒作用,使HBeAg阴转率提高。结论:复方仙灵脾冲剂对降低血清sIL-2R、提高外周血T淋巴细胞中CD_4/CD_8及HBeAg阴转有一定作用。
Aim: sIL-2R. CD4/CD8 in T lymphcytes and HBeAg in the blood were observed in patients with chronic hepatitis B treated by Compound Epimedium Brevicornum (CEB). Methods: sIL-2R was determined by ELISA, T lym-phcyte subpopulation in the blood was determined by immunofluorescence and HBeAg was determined by ELISA. Re-stlts; it was found that sIL-2R was evidently decreased in patients treated by CEB compared with the contrast and there was a significant difference (P<0. 05). that T lymphcyte subpopulation was improved on a higher CD4/CD8 ratio than the contrast and there was a specially significant differnce (P<0.01 ), and that there was a effect on antivirus of improving HBeAg disappearing. Conclusion; These findings indicate that CEB could affect sIL-2R decreasing. CD4/CD8 ratio increasing and HBeAg disappearing.
出处
《中西医结合肝病杂志》
CAS
2000年第1期14-16,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
关键词
复方仙灵脾冲剂
SIL-2
E抗原
乙型肝炎
Compound Epimedium Brevicornum Soluble Interleukin-2 Receptors T Lymphcyte Subpopulation HBeAg
