摘要
非创伤性股骨头坏死早期保守治疗方法甚多,但尚缺乏一种成熟有效的治疗方法。基因治疗非创伤性股骨头坏死是近年来新型的治疗方法,本文就该病的发病机制、分子生物学基础、外源性治疗基因与载体选择等方面研究的相关进展及存在问题展开综述,讨论了研究的有关问题及对策,并就研究前景进行了展望。
There are many methods of conservative treatment for early non-traumatic osteonecrosis of femoral head, but still lack of a mature and effective treatment. Gene therapy is a new treatment method for non-traumatic osteonecrosis of femoral head in recent years. This article showed that the non-traumatic osteonecrosis of femoral head related to progress and problems on pathogenesy,molecular biology foundation, exogenous theoretical gene, carrier selection and so on, discussed some prob- lems and countermeasure and future applications.
出处
《中国骨伤》
CAS
2012年第6期525-529,共5页
China Journal of Orthopaedics and Traumatology
基金
国家自然科学基金(面向项目)(编号:81072821)~~
关键词
股骨头坏死
治疗
基因
综述文献
Femur head necrosis
Therapy
Genes
Review literature
