摘要
目的分析大脑中动脉粥样硬化性脑梗死相关危险因素的差异,探讨其潜在病因。方法收集136例大脑中动脉粥样硬化性急性脑梗死患者的DWI资料,据梗死灶的形态表现分为三种类型:大皮层、小皮层(直径<1cm)、深部梗死。分析三种类型的危险因素。结果调整影响因素,老年人独立的和小皮层病灶有关;年轻人、快速增长的血葡萄糖水平和入院后外周血白细胞增高独立的和大皮层病灶有关。结论年龄、血葡萄糖水平、白细胞数量能预测大脑中动脉粥样硬化性急性脑梗死的梗死灶形态,强化这些方面的检查,有利于指导治疗,改善预后。
Objective To analyze the risk factors with acute ischemic stroke in MCA atherosclerosis,and to explore the potential causes.Methods The DWI data of 136 patients were prospectively assessed,we divided the patients into three stroke lesion pattern：large cortical,small（ 1 cm in diameter） cortical,and deep pattern.Independent factors for each stroke phenotype were evaluated using logistic regression.Results After adjusting for covariates,older age（OR 1.052,95%CI 1.022-1.082）were independently associated with the small cortical pattern.In contrast,younger age（OR 0.952,95 %CI 0.921-0.983）,and admission peripheral WBC counts（OR 1.131,95 % CI 1.101-1.269） were independently associated with the large cortical pattern.Conclusion Age,hyperglycemia and WBC counts can predict atherosclerotic stroke lesion pattern,so we should strengthen the inspection of these areas,in order to improve stroke outcome.
出处
《中国实用医药》
2012年第15期41-43,共3页
China Practical Medicine
