摘要
目的:研究鼠曲草属植物秋鼠曲草的化学成分。方法:利用硅胶柱色谱、ODS反相柱色谱、Sephadex LH-20等手段进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果:从秋鼠曲草中分离得到10个化合物,分别鉴定为:二十四烷酸(1)、5-羟基-3,6,7,8-四甲氧基黄酮(2)、β-谷甾醇(3)、5-羟基-3,6,7,8,4'-五甲氧基黄酮(4)、5-羟基-3,6,7,8,3',4'-六甲氧基黄酮(5)、芹菜素(6)、木犀草素(7)、槲皮素(8)、木犀草素-4'-O-β-D-葡萄糖苷(9)、槲皮素-4'-O-β-D-葡萄糖苷(10)。结论:以上化合物均为首次从该植物中分离得到,化合物5为首次从该属植物中分离得到。
Objective ：To research the chemical constituents from Gnaphalium hypoleucum. Methods：Compounds were separated by using silica gel, ODS, Sephadex LH-20 chromatography and their structures were elucidated by means of spectral data analysis. Re- suits ： Ten compounds were isolated and identified as tetracosanoic acid （ 1 ）, 5-hydroxy-3,6,7,8-tetramethoxyflavone （2） ,β-sitosterol （ 3 ）, 5-hydroxy-3,6,7,8,4＇-pentamethoxyflavone （ 4 ）, 5-hydroxy-3,6,7,8,3＇, 4＇-hexamethoxyflavone （ 5 ）, apigenin （ 6 ）, luteolin （ 7 ）, quercetin （ 8 ）, luteolin-4＇-O-β-D-glucoside （9）, quercetin-4＇-O-β-D-glucoside （ 10 ）. Conclusion： All of these compounds are iso- lated from this plant for the first time. Compound 5 is isolated from the genus for the first time.
出处
《中药材》
CAS
CSCD
北大核心
2012年第4期566-568,共3页
Journal of Chinese Medicinal Materials
关键词
秋鼠曲草
化学成分
黄酮
Gnaphalium hypoleucum DC.
Chemical constituents
Flavonoids
