摘要
目的探讨尤瑞克林注射液对急性脑梗死患者血清C-反应蛋白(CRP)及尿酸(UA)水平的影响。方法将发病48h内的急性脑梗死患者80例随机分为观察组和对照组,每组40例。对照组给予常规治疗,观察组在常规治疗基础上加用尤瑞克林,共10d。2组治疗前后分别测定血清CRP和UA水平,并观察神经功能缺损评分变化。结果治疗后2组CRP、UA水平和神经功能缺损评分均较治疗前下降,但观察组各项指标下降均较对照组明显(P<0.05)。治疗期间无明显不良反应发生。结论尤瑞克林治疗急性脑梗死疗效显著,且能显著降低急性脑梗死患者血清CRP及UA水平。
Objective To investigate the effect of urinary kallidinogenase on the changes of serum C-reactive protein（CRP） and uric acid（UA）in patients with acute cerebral infarction.Methods Eighty acute cerebral infarction patients were randomly divided into two groups：treatment group and control group.Patients in both two groups were given routine treatment.Urinary kallidinogenase was additionally used in the treatment group.The neurologic impairment score and serum levels of CRP and UA pre-and post-treatment were compared between the two groups.Results Neurologic impairment scores of patients in the two groups were all improved,but the treatment group was better than control group（P0.05）.Serum levels of CRP and UA reduced in the two groups,but the treatment group was significantly lower than control group（P0.05）.There was no obvious adverse reaction.Conclusion Urinary kallidinogenase is safe and effective in the treatment of acute cerebral infarction,and can significantly reduce the serum concentrations of CRP and UA.
出处
《中国实用神经疾病杂志》
2012年第11期8-10,共3页
Chinese Journal of Practical Nervous Diseases
关键词
尤瑞克林
急性脑梗死
C-反应蛋白
尿酸
Urinary kallidinogenase
Acute cerebral infarction
C-reactive protein
Uric acid
