摘要
本文采用外周血淋巴细胞微核检测法来观察三品对受治患者遗传物质的影响,并用放射治疗患者进行对照。测定结果:三品治疗前组平均微核出现率为1.1‰,治疗结束组为0.9‰,随访复查组为0.9‰,三者间经统计学处理,无显著差异(P>0.05);而放射治疗前组为1.2‰,治疗结束组为4.6‰,两者间具有非常显著差异(P<0.01)。结果表明三品锥切疗法未见明显损伤遗传物质的效应。对于早期宫颈癌的治疗,本疗法优于放射治疗。
The impact of 'Sanpin' on genetic material of patients with chronic cervical diseases treated by 'Sanpin' conization was investigated by determining micronucleus rate in peripheral lymphocytes. The mean micronucleus rates were 1.1‰ in untreated group, 0.9‰ in immediate post-treatment group, and 0.9‰ in follow-up group respectively. No significant differences were found among the three groups. In patients treated with radiotherapy the mean micronucleus rates were 1.2‰ in the group before treatment and 4.6‰ in post-treatment group, with a statistical significant difference (P<0.01). As compared with radiotherapy 'Sanpin' conization did not show any damage to genetic elements in patients, therefore it could be the treatment of choice for patients with early cervical cancer rather than radiotherapy.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1990年第6期336-338,共3页
Chinese Journal of Clinical Oncology
关键词
三品锥切
宫颈癌
淋巴细胞
“Sanpin” conization
Chronic cervical diseases
Micronucleus
Peripheral lymphocytes
