摘要
目的:观察肝脾舒合剂治疗肝热脾虚型便秘型肠易激综合征(C-IBS)的临床疗效。方法:将60例肝热脾虚型C-IBS患者分两组,治疗组40例予GPS合剂治疗,对照组20例予莫沙必利治疗,疗程8周。观察两组临床疗效、主要症状评分和生活质量评分变化。结果:治疗组总有效率为90.00%,对照组为60.00%,两组比较差异有显著性意义(P<0.05);治疗后两组主要症状积分均有降低(P<0.05),且治疗组低于对照组(P<0.05);两组患者生活质量均有不同程度改善(P<0.05),且治疗组改善优于对照组(P<0.05)。结论:肝脾舒合剂能改善肝热脾虚型C-IBS患者临床症状,提高其生活质量。
Objective： To observe the clinical efficacy of ＂ Ganpishu Mixture＂ in the treatment of constipation-predominant irritable bowel syndrome（C-IBS） of liver heat and spleen deficiency. Methods： Sixty subjects were randomized into two groups： treatment group in which 40 cases were treated with ＂Ganpishu Mixture＂ and control group in which 20 cases were treated with mosapride citrate tablets, with a course of 8 weeks. The clinical efficacy, the main symptom scores and quality of life scores were observed. Results： The total effective rate was 90.00% in the treatment group and 60.00% in the control group, with a striking difference between the two groups （ P 〈 0. 05 ）. After treatment, the main symptom scores were decreased in both groups （ P 〈 0.05 ）, with more significant decrease in the treatment group than in the control group （ P 〈 0.05 ） ; the quality of life was improved in both groups （ P 〈 0.05 ）, with more significant improvement in the treatment group than in the control group （ P 〈 0.05 ）. Conclusion： ＂Ganpishu Mixture＂ can improve the clinical symptoms and enhance the life of quality in the treatment of C-IBS of liver heat and spleen deficiency.
出处
《上海中医药大学学报》
CAS
2012年第3期41-43,共3页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
上海市卫生局中医药基金项目(2010J003A)
关键词
肠易激综合征
便秘型
肝脾舒合剂
Irritable bowel syndrome
constipation predominance
＂Ganpishu Mixture＂
