摘要
目的观察电针"呼循穴区"对心律失常大鼠的心电图及血浆环磷酸腺苷(cAMP)、环磷酸鸟苷(cGMP)水平的影响。方法采用BaCl2诱发大鼠心律失常模型,电针大鼠呼循穴区,观察实验前后各时刻大鼠心电图变化,检测干预后大鼠血浆cAMP、cGMP含量,并与电针额旁1线,舌下静脉注射0.5%利多卡因进行对比。结果电针呼循穴区能减慢心律失常大鼠心率、缩短复律时间,降低血浆cAMP、cAMP/cGMP水平,电针呼偱穴区与额旁1线效果相当,0.5%利多卡因效果最强。结论电针呼循穴区对心律失常大鼠有明显的改善作用,其作用机制可能与经络、自主神经系统,血浆cAMP、cGMP水平有关。
Objective： To observe the effects of electro-acupuncture （EA） in arrhythmia rats via ECG,plasma cAMP and cGMP levels. Methods： Experimental arrhythmia model was induced by BaCl2 in rats with EA on Huxun point area or lateral line 1 of fore-head or intravenous inject lidocaine. Some indices were observed such as the ECG,the cAMP and the cGMP. Results： After the EA on Huxun point area,the heart rate and the car- dioversion time were decreased. Levels including cAMP and cAMP / cGMP were reduced. The effect of EA on Huxun point area was similar to EA on lateral line 1 offore-head. Moreover,the intravenous inject lidocaine had the strongest effect. Conclusion： EA on Huxun point area has an obvious curative effect in arrhythmia rats. Its mechanism maybe related to the meridians ,the autonomic nervous system ,the cAMP and the eGMP.
出处
《中国中医急症》
2012年第6期908-910,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
国家大学生创新性实验计划项目
关键词
呼循穴区
电针
心律失常
Huxun point area
Electro acupuncture
Arrhythmia
