摘要
目的观察补脾益肾升血丸治疗肾性贫血的临床疗效。方法将辨证为脾肾亏虚、瘀血内停证的维持性血液透析的尿毒症患者随机分为两组,治疗组给予补脾益肾升血丸,对照组给予重组人红细胞生成素,两组均观察2个疗程(8周)。对中医证候的变化及HB、RBC、HCT、铁蛋白等指标进行观察。结果治疗组中医证候有效率明显优于对照组,两组总有效率相近,且治疗组高血压、高血钾发生率显著低于对照组,治疗组铁蛋白明显升高,对照组铁蛋白明显降低;治疗组无明显不良反应发生。结论补脾益肾升血丸治疗肾性贫血安全有效,同时可治疗缺铁性贫血,提高生存质量。
Objective： To discuss the clinical effect of Bupiyishenshengxue Pill in the renal anemia. Methods： After maintenance hemodialysis for 4 weeks,patients with the spleen and kidney deficiency syndrome and the blood stasis syndrome were divided randomly into 2 groups. The treatment group was given the Bupiyishenshengx- ue Pill and the control group was used the recombinant human erythropoietin. After the treatment period for 8 weeks,some indices were observed including the TCM syndrome,the HB,the RBC and so on. Results： The effec- tive rate of TCM syndrome in the treatment group was superior to that in the control group. Howevere, there was no statistical difference in the total effective rates of 2 groups. These incidences of hypertension and hyperkalemia in the treatment group were lower than those in the control group. Meanwhile ,the ferritin level was increased in the treatment group, but that was decreased in the control group. There was no adverse reaction in the treatment group. Conclusion： Bupiyishenshengxue Pill in treatment of renal anemia is safe and effective. At the same time, it can treat the iron deficiency anemia and improve the overall quality of life.
出处
《中国中医急症》
2012年第6期878-880,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
山东省烟台市科学技术发展计划项目(2010150)
