摘要
核转录因子-κB(Nuclear Factor-Kappa B,NF-κB)是一种重要的转录因子,近年来的研究表明,在炎症反应、免疫反应及细胞凋亡中起重要作用,在肝缺血再灌注损伤过程中亦至关重要。现就NF-κB及其在肝缺血再灌注损伤过程中的作用机制作一综述。
Nuclear faetor-kappaB (NF-κB) is a major transcription factor. Recent studies have shown that NF-κB plays a crucial role not only in inflammation, immune response and apoptosis, but also in the development and process- ing of pathological liver isehemia and reperfusion injury. This review foeuses on its detailed meehanism.
出处
《胃肠病学和肝病学杂志》
CAS
2012年第6期583-585,共3页
Chinese Journal of Gastroenterology and Hepatology
基金
黑龙江省自然科学基金面上项目(C1602)
关键词
NF-ΚB
肝缺血再灌注损伤
Nuclear factor-kappa B
Liver ischemia and reperfusion injury