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系膜增生性肾小球肾炎患者血清IL-6、IL-10、IL-13检测的临床意义 被引量:3

Clinical significance of determination of serum IL-6,IL-10 and IL-13 levels in patients with mesangial proliferative glomerulonephritis
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摘要 目的探讨系膜增生性肾小球肾炎治疗前后血清IL-6、IL-10、IL-13水平的变化及意义。方法测定70例患者治疗前后血清IL-6、IL-10、IL-13的含量,并与30例正常健康者作比较。结果激素敏感组系膜增生性肾小球肾炎患者在治疗后血清IL-6、IL-10、IL-13水平较治疗前降低(P<0.05)。结论血清IL-6、IL-10、IL-13水平变化在一定程度上可提示病情变化,监测治疗效果。 Objective To investigate the changes and clinical significance of serum interleukin-6(IL-6),interleukin-10(IL-10) and interleukin-13(IL-13) levels before and after treatment in pediatric patients with mesangial proliferative glomerulonephritis.Methods Serum IL-6,IL-10 and IL-13 levels were determined in 70 patients before and after treatment and 30 controls.Results After treatment,the serum IL-6,IL-10 and IL-13 levels in the steroid sensitivity group were lower than those before treatment(P0.05).Conclusion The changes of IL-6,IL-10 and IL-13 levels can reflect the change of disease condition and monitor the therapeutic effects.
机构地区 泰安市中心医院
出处 《现代医药卫生》 2012年第10期1478-1479,共2页 Journal of Modern Medicine & Health
关键词 白细胞介素6 白细胞介素10 白细胞介素13 肾小球肾炎 膜增生性 Interleukin-6 Interleukin-10 Interleukin-13 Glomerulonephritis membranoproliferative
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