摘要
目的了解汉中地区2009年-2011年甲型流感流行情况，为甲型流感的预防控制提供科学依据。方法对国家级流感监测哨点医院汉中市中心医院及汉中市11县区疾病预防控制中心送检的鼻咽拭子样本采用Real—timeRT-PCR方法进行甲型流感病毒核酸检测，并对检测结果进行分析。结果1396份样本中甲型流感病毒阳性469份，阳性率为33．60％，其中甲型H1N1占92．32％、季节性H3N2型占5．97％、季节性H1N1型占0．64％、未分型占1．07％。男、女阳性率分男lI为32．30％（251／777），35．22％（218／619），阳性率差异无性剐问统计学意义（χ^2=1．31，P＞0．05）。5个年龄组的阳性率分别为：O-4岁组20．97％，5-14岁组41．og％，15-24岁组40．32％，25～59岁组30．41％，≥60岁组23．64％，各年龄组阳性率差异有统计学意义（χ^2=48．69，P〈0．05）。结论汉中地区甲型流感流行主要发生在冬季，其优势株为甲型H1N1流感病毒，季节性H3N2流感、季节性H1N1流感病毒在每年9月至次年3月呈散发的形式存在。学龄儿童和青少年将是今后甲型流感的重点防控对象。
Objectives To study the prevalence of influenza A virus in Hanzhong area from 2009 to 2011 and to provide basic information to prevent from and control influenza epidemics. Methods Nasopharyngeal swabs from patients with symptom of influenzalike illness （ILI） in a sentinel hospital（Hanzhong center hospital） and samples submitted by Centers for Disease Control and Prevention in 11 area counties were collected. Influenza A virus was detected and further subtyped using realtime RT-PCR. The statistical analysis of the results was made. Results In total, 1 396 swabs were collected and 469 were positive for the influenza A virus. The positive rate was 33. 600/oo. Pandemic A（HIN1） accounts for 92. 32% ,and that was followed by seasonal A （H3N2）（5.97%）, seasonal A （H1N1） （0. 64,%）,and unknown subtype （1.07%）. The positive masculine rate was 32. 300% ,and the feminine one was 35. 220%. No gender differences in the infectivity of Pandemic A（H1N1） （χ^2 = 1.31, P〉0. 05）. Positive rate of the five age groups：0-4 group was 20. 970/oo ,5-14 group was 41.09% ,15-24 group was 40. 32% ,25-59 group was 30. 41% ,≥ 60-group was 23.64%. Statistical significance（χ^2=48. 69, P〈0. 05） was found in the positive rate difference of each age group. Conclusion This analysis shows thatinfluenza A is mainly popular in winter in Hanzhong area,and pandemic A （H1N1） was the dominant. Seasonal A （H3N2） and seasonal A （H1N1） intermittently e- merged from September to March of year. School age children and teenagers will be the focus people for being prevented from and controlled influenza A.
出处
《现代检验医学杂志》
CAS
2012年第2期125-127,共3页
Journal of Modern Laboratory Medicine
关键词
甲型流感
病毒核酸
监测
influenza A virus
virus nucleic acid
surveillance
