摘要
目的 综合分析影响肺鳞癌预后的临床及社会心理等各种因素 ,建立肺鳞癌患者的预后指数 (PI)模型 ,为临床上选择治疗方案、判断患者的预后及开展社会心理健康教育提供参考。方法 对 3 0 8例肺鳞癌患者进行全程随访 ,运用Cox回归模型对各种预后因素进行分析。结果 从 69项预后因素中确定病后情绪、初治时手术方式、病后饮食状况、初治时合并其它疾病、社会支持、初治时单纯放疗方式及复治次数 7项为影响肺鳞癌预后的主要因素。其中病后情绪与生存期的关系最密切 ,初治时手术方式次之。结论 建立预后指数模型 ,可据此预测患者的预后 ,其灵敏度为 89.4% ,可靠性为 86.1%。
Objective Multivariate analysis was made for patients with lung squamous cell cancer.Prognosis Index(PI) model has been established.These information could provide scientific reference for treatment of patients,evaluation of prognosis and health education.Methods 308 patients with lung squamous cell cancer were followed up.Using Cox regression model,a multivariate analysis was made.Results Among 69 factors,only emotional state operation,type,diet situation,the number of suffering from other diseases,social suport,type of radiotherapy,the times of treatment showed a high statistical significance in prognosis.Emotional state is the most important factor which influenced survival time.Conclusion PI may be calculated according to patient's individual features,which can be used as evaluation of prognosis.It's sensitivity and reliability achieved 89.4% and 86.1%.
出处
《实用癌症杂志》
2000年第3期294-296,共3页
The Practical Journal of Cancer
关键词
肺鳞癌
预后
COX回归模型
Lung squamous cancer
Prognosis
Cox regression model
