摘要
研究并确定了醋酸氯已定与甲酚红的荷移反应条件。在乙醇-丙酮介质中形成1：1型络合物，其λmax=455nm，醋酸氯已定浓度在0～80mg/L范围内呈线性关系；表观摩尔吸光系数为1．08×104L·mol-1·cm-1；桑德尔灵敏度是0．0345μg·cm-2；相对标准偏差小于1％（n＝8），回收率符合要求。
The charge transfer reaction between chlorhexidine acetate and cresol red in alcohol-acetone solution was studied specbophotometrically. The apparent molar absorptivity is 1 .08×104L·mol-1·cmat 455 nm. The Beer's law was obeyed in the range of 0～80 mg/L of chlothexidine acetate. The composition of complex is 1: 1. The proposed was applied to the determination of chlothexidine aretate with satisfactory results.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2000年第3期365-367,共3页
Chinese Journal of Analytical Chemistry
关键词
醋酸氯己安
甲酚红
分光光度法
药物分析
Charge transfer reaction , chlorhexidine acetate, cresol red, spectrophotometry
