摘要
骨性关节炎是一种退化性关节疾病,以关节软骨的降解、关节边缘骨赘的形成和滑膜病变为特征,以往的研究和治疗重点在关节软骨病变,而最新研究显示滑膜的炎症在骨关节炎中起重要作用,滑膜炎症和滑膜相关的致炎因子诱导的关节软骨的降解和破坏,促进了骨关节炎的发展。滑膜病变在骨关节炎中的表现日益突出,而针对滑膜病变的治疗将成为一个新的靶点。
Osteoarthritis is a degenerative joint disease,with the characters of degradation of articular cartilage,the formation of the joint marginal osteophyte and synovium lesions. Previous studies have focused on the treatment of articular cartilage lesions. In recent years,new research in shows synovial inflammation plays an important role in OA. Synovium lesions and synovial inflammation-related factors induced the degradation and destruction of articular cartilage,and promoted the development of osteoarthritis. The role of synovial lesions in osteoarthritis is increasingly prominent,and the treatment for synovial lesions will become a new target. So this paper reviews the various manifestations of synovial in osteoarthritis.
出处
《中国骨伤》
CAS
2012年第5期442-444,共3页
China Journal of Orthopaedics and Traumatology
基金
上海市教委课题资助(编号:.08cz041)
上海市教委高校创新团队课题资助[沪教委科(2009)6号]
上海普陀区科委卫生系统自主创新基金资助~~
关键词
骨关节炎
滑膜
综述文献
Osteoarthritis Synovial membrane Review literature
