摘要
目的:探讨老年患者骨质疏松与动脉钙化之间的相关性。方法:对123例老年住院患者采用双能X线吸收法测定腰椎正位(L1～4)、股骨颈(左股骨、右股骨)骨密度T值,分析骨密度与冠状动脉钙化的关系;同时按AJ-130、Volume-130两种评分标准进行心脏冠状动脉钙化评分;将123例患者按年龄段分为A、B、C三组各41例,观察比较各年龄段骨量减少、骨质疏松、动脉钙化情况。结果:骨量减少、骨质疏松者冠状动脉钙化严重程度显著高于骨量正常者(P<0.01),钙化评分与骨密度呈负相关;骨量减少、骨质疏松、动脉钙化严重程度随年龄增加呈显著上升趋势(P<0.01)。结论:老年骨质疏松患者较非骨质疏松者更易发生动脉钙化病变,同时存在动脉钙化病变者也易致骨量丢失,提示骨质疏松与动脉钙化之间可能存在共同危险因素。
Objective： To explore the correlation between osteoporosis and arterial calcification in elderly patients. Methods： The dual energy X - ray absorption method was used for the determination of T value of bone mineral density of lumbar spine （ Lt -4 ）, femoral neck （ the left and right femurs） of 123 hospitalized elderly patients, the relationship between bone mineral density and coronary artery calcifi- cation was analyzed; meanwhile the coronary artery calcification was evaluated in the light of AJ - 130 and Volume - 130 scoring criteria. Then 123 patients were divided into group A, B and C according to age differences（41 patients in each group}. The osteopenia, osteopo- rosis and arterial calcification in different ages was observed and compared. Results- The severity of osteopenia, osteoporosis and coronary artery calcification was significantly higher in the patients than that of those who had normal bone mass （ P 〈 0.01 ） ; the calcification score negatively correlated with BMD ; the severity of osteopenia, osteoporosis and arterial calcification significantly increased with increasing age （ P 〈 0.01 ）. Conclusion： The elderly patients with osteoporosis are more susceptible to artery calcification and presence of arterial calcifi- cation also causes bone loss, indicating that the common risk factors may exist between osteoporosis and arterial calcification.
基金
山东省医药卫生科研项目(2007年第BZ12号)
关键词
老年
骨量减少
骨质疏松
动脉钙化
Osteopenia
Old age
Osteoporosis
Arterial calcification
