摘要
目的了解医院2011年临床感染性标本病原菌的分布及其对常用抗菌药物的耐药性。方法常规培养、分离并鉴定细菌,用纸片扩散法进行病原菌药敏试验。结果 2011年本科室共分离出560株病原菌,以革兰阴性(G-)杆菌为主,占70.4%;革兰阳性(G+)球菌占21.1%;真菌占8.5%。在G-杆菌中,大肠埃希菌居首位,铜绿假单胞菌次之;在G+球菌中,金黄色葡萄球菌分离率最高。所有病原菌对常用抗菌药物耐药率较高。产超广谱β-内酰胺酶(ESBLs)菌株在大肠埃希菌和克雷伯菌属中分离率分别为43.0%、47.2%。结论医院感染病原菌分布广泛,耐药现象严重,耐甲氧西林葡萄球菌及产ESBLs大肠埃希菌和克雷伯菌分离率较高。应加强细菌耐药性监测,指导临床医生合理使用抗菌药物。
Objective To investigate the distribution and drug resistance of pathogenic bacteriain of clinical infectious specimens 2011. Methods Bacteria was conventionally cultured,separated and identified with scraps of paper diffusion method （K B method） for pathogens drug sensitivity test. Results In 2011,560 strains of pathogenic bacteria were separated out, in which gram negative bacteria （G-） was given priority to 70. 4%, gram positive coccus （G＋） was 21. 1 %, and fungi was 8. 5%. In gram negative bacilli, escherichia coli strains accounted for the most, pseudomonas aeruginosa was the second. And in G＋ coccus,the separation rate of staphylococcus aureus （SA） was the highest. Drug resistance rate of all the pathogenic bacteria for the common antibacterials was high. The separata taion rate of producted extended-spectrum β- lactamase （ESBLs） strains in escherichia coli and klebsiella were 43.0% and 47.2%, respectively. Conclusion Nosocomial infectious pathogens are widely distributed, and it is serious for drug resistance. The separatataion rate of MRS, ESBLs, and klebsiella which can produce producted is high. We should strengthen the bacterial resistance monitoring,and guide clinical doctors for rational use of antibacterials.
出处
《检验医学与临床》
CAS
2012年第10期1193-1194,1197,共3页
Laboratory Medicine and Clinic
关键词
病原菌
抗菌药物
耐药率
antimicrobial
resistant
pathogens
