期刊文献+

中西医结合治疗创伤性关节炎临床观察 被引量:2

Clinical observation of combination therapy of Chinese and western medicine on the treatment of traumatic arthritis
暂未订购
导出
摘要 目的观察中药熏洗配合西医常规保守治疗创伤性关节炎(TA)的临床疗效。方法将108例TA患者随机分为2组。对照组54例采用西医常规保守治疗;治疗组54例在对照组治疗基础上加用中药熏洗。2组均以7 d为1个疗程,2个疗程后观察治疗前后关节液中一氧化氮(NO)、超氧化物歧化酶(SOD)及丙二醛(MDA)含量变化,并进行疗效比较。结果治疗组治疗后总有效率88.0%,对照组总有效率75.9%,2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效明显优于对照组;2组治疗后关节液中NO、SOD及MDA的含量与本组治疗前比较差异均有统计学意义(P<0.05);治疗组治疗后关节液中NO、SOD及MDA的含量与对照组比较差异均有统计学意义(P<0.05),治疗组改善优于对照组。结论中药熏洗配合常规抗炎镇痛西药治疗TA临床疗效优于单纯采用西药治疗,可有效缓解或消除关节疼痛、肿胀等症状,缩短病程,且安全可靠。 Objective To observe the effect of fumigation of Chinese herb combined with conventional western conservative treatment on traumatic arthritis(TA).Methods 108 cases of TA were randomly divided into two groups.Patients in control group(n=54) were treated by conventional western medical therapy.Patients in treatment group(n=54) were treated by fumigation of Chinese herb combined with conventional western conservative treatment.The course was seven days in two groups.The changes of NO,SOD and MDA in joint fluid were observed after two courses.Results There was obvious difference between two groups on the total effective rate(88.0%,75.9%,P0.05).There were obvious differences between before and after treatment on N0,SOD and MDA in joint fluid in two groups(P0.05).There were obvious differences between two groups on NO,SOD and MDA in joint fluid after treatment(P0.05).Conclusion The effect of fumigation of Chinese herb combined with conventional western medicine treatment was superior to that of only conventional western medicine treatment.Combination therapy of Chinese and western medicine can effectively mitigate or eliminate joint pain,swelling and other symptoms,shorten the course,and has safety.
作者 王海平
出处 《河北中医》 2012年第3期387-389,共3页 Hebei Journal of Traditional Chinese Medicine
关键词 骨关节炎 外治法 中西医结合疗法 Ostearthritis External treatment Combination therapy of Chinese and western medicine
  • 相关文献

参考文献8

二级参考文献64

  • 18.Bonnin JG.Injuries to the ligments of the ankle.J Bone Joint Surg(Br),1965,47:609
  • 29.Lambert KL.The weight-bearing function of the fibula:a strain gauge study.J Bone Joint Surg(Am),1971,53;507
  • 3Blanco FJ, Lotz M. IL-1-induced nitric oxide inhibits chondrocyte proliferation via PGF2[J]. Exp Cell Res,1995,318: 319-325.
  • 4Blanco FJ,Galdo F,de Toro FJ,et al. Osteoarthritis chondrocytes die by apoptosis,a possible pathway for osteoarthritis pathology [J ]. Arthritis Rheum, 1998, 41:284-289.
  • 5Hauselmann HJ,Evans CH,Michel DA,et al. Differences in nitric oxide product by superficial and deep human articular chondrocytes: implications for proteoglycan turnover in inflammatory joint disease[J]. J Immunol, 1998,160:1448.
  • 6Cao M,Evans CH,Stefanovic-Racic M, et al. Nitric oxide inhibits the synthesis of the Ⅱ collagen without altering CO12A1 mRNA abundance prolyl hydroxylase as a possible target [J]. Biochem J, 1997,324: 305 310.
  • 7Pelletier J-P,Jovanovic D,Julio C. Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase [J]. Arthritis Rheum, 1998,41 : 1275- 1286.
  • 8Panasiuk AF, Laroshuk GV, MItrovich D. Effect of free radicals on proliferation and metabolism of chondrocytes and on sensitivity of a cellular monolayer to proteases [J]. Vopr Med Khim, 1995,41:19- 22.
  • 9Kvam BJ,Fragonas E,Degrassi A,et al. Oxygen-derived free radical (ODFR)action on hyaluronan (HA), on two HA ester derivatives ,and on the metabolism of articular[J]. Lancet, 1994,343:1471- 1472.
  • 10Bukhardt H,Schwingel M,Menninter H,et al. Oxygen radicals as effectors of cartilage destruction[J].Arthritis Rheum, 1986,29: 379 - 386.

共引文献106

同被引文献16

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部