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Caspase家族与颞叶癫痫神经元凋亡 被引量：3

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摘要 颞叶癫痫（temporal lobe epilepsy，TLE）是指与颞叶皮层或颞叶内侧海马等结构发生相关病理改变导致的癫痫，临床主要表现为复杂部分性发作，以海马硬化为典型病理特征。以往研究认为神经元坏死是海马硬化的主要原因，但是近年的研究表明海马硬化可能与神经元的凋亡有关。动物实验证明短暂或持续的癫痫发作后可观察到实验动物脑内神经元的凋亡和检测到多种凋亡相关基因的表达。
作者 宋海洋 金澎
机构地区 青岛大学医学院附属医院神经外科
出处 《中华神经外科疾病研究杂志》 CAS 2012年第2期187-189,共3页 Chinese Journal of Neurosurgical Disease Research
关键词 半胱氨酸 颞叶癫痫 神经元
分类号 R742.1 [医药卫生—神经病学与精神病学]
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参考文献15

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二级参考文献38

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共引文献47

同被引文献30

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引证文献3

二级引证文献8

中华神经外科疾病研究杂志
2012年 第2期

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