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2型糖尿病并发冠心病发病机制及治疗 被引量:8

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摘要 根据国际糖尿病联盟(IDF)统计,糖尿病患者以每年新发700万的速度迅猛增长,估计到2030年全球将有5亿人患糖尿病.最新流行病学统计中国现有9240万成年人患有糖尿病,约1.5亿成年人处于糖尿病前期.大量流行病学资料表明,糖尿病患者伴发冠心病者均较同年龄、同性别的非糖尿病对照组高,在女性患者中高约4.5倍,在男性患者中高约2倍.在2型糖尿病初诊时,约50%患者已经伴发冠心病,即糖尿病前期葡萄糖调节受损(IGT)时冠状动脉粥样硬化就已经发生发展.而糖尿病患者心肌梗死的发生率比非糖尿病患者高3~5倍,有70%以上的糖尿病病人死于心血管并发症或伴随症[1],心肌梗死是2型糖尿病(T2DM)患者的首要致死病因.美国国家胆固醇教育计划成人治疗指南l(NcEP-ATP111)中将糖尿病列为冠心病的等危症.
出处 《中国社区医师(医学专业)》 2012年第12期165-166,共2页
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