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高压氧对脑梗塞急性期血浆α颗粒膜蛋白含量的影响

Effect of hyperbaric oxygen on GMP-140 levels in plasma during the acute period of cerebral infarction
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摘要 目的 探讨高压氧对脑梗塞急性期病人血浆 α颗粒膜蛋白 ( GMP-1 4 0 )含量变化的机理。方法 应用双夹心放免测定法 ,定量测定两组脑梗塞急性期病人治疗前和治疗 2 0天后的血浆 GMP-1 4 0含量。结果  1脑梗塞急性期患者治疗前的血浆 GMP-1 4 0明显增高 ,与正常值相比有非常显著性差异 ;2治疗 2 0天后 ,高压氧组与对照组相比 ,血浆 GMP-1 4 0含量明显下降 ,两组相比有显著性差异。结论 对于脑梗塞急性期患者 ,在进行常规药物治疗同时 ,加用高压氧治疗 ,可明显降低血小板的活性。 Objective To investigate the effect of hyperbaric oxygen on the treatment of cerebral infarction Methods The levels of plasma GMP 140 were measured by using of double antibodies sandwich radioimmunoassay before and 20th day after the initiating of hyperbaric oxygen treatment Results The levels of plasma GMP 140 were significantly higher than normal during the acute period of cerebral infarction before the treatment,and they were significantly lower in the hyper baric oxygen treated group than in the control group after 20 days treatment Conclusions During acute period of cerebral infarction, byper baric oxygen therapy can significantly reduce the activity of blood platelets
出处 《北京医学》 CAS 北大核心 2000年第2期100-102,共3页 Beijing Medical Journal
关键词 脑梗塞 血浆 Α颗粒膜蛋白 高压氧治疗 Hyperbaric oxygen Cerebral infarction GMP 140
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