摘要
目的:总结急性光气中毒的临床特点。方法:收集23例急性光气中毒患者的临床资料,对发病时间、初发临床表现、诊治结果进行综合分析。结果:重度组的潜伏期显著短于轻度组(P<0.01)。光气中毒主要初发症状为咳嗽(82.61%)、胸闷(69.57%)等呼吸道症状。重度组呼吸频率、心率、外周血白细胞计数、中性粒细胞百分比、肌酸激酶及其同工酶、肌钙蛋白等实验室检查指标均高于轻、中度组(P<0.05～P<0.01)。23例患者均存活。结论:急性光气中毒的临床表现主要集中在呼吸系统;根据病情轻重及早短程给予适当剂量糖皮质激素治疗,合理呼吸支持是防止病情恶化、保证抢救成功的关键。
Objective：To sum up the clinical features of acute phosgene poisoning.Methods：Twenty three cases of acute phosgene poisoning in our hospital during Jan.6 to 8 in 2011were gathered.The latency phase,onset clinical manifestation,results of diagnosis and treatment were analyzed.Results：The latency phase in sever group was significantly shorter than in the other groups（mild group）（P〈0.01）.The main onset clinical manifestations were cough（82.61%）,oppressive sensation over the chest（69.57%）.The respiratory rate,heart rat,levels of leukocyte count,neutrophil number,the value of creatine kinase,creatine phosphokinase-isoenzyme-MB and cardiac troponin-I in sever group was significantly greater than in the other groups（mild or moderately group）（P〈0.05 to P〈0.01）.There were no deaths.Conclusions：The primary clinical symptom of acute phosgene poisoning mainly concentrated on the respiratory system.Each patient receives moderate-dose methylprednisolone and respiratory supporting according to the severity of the disease in the early stage,which is the key point for successful rescue.
出处
《蚌埠医学院学报》
CAS
2012年第4期404-406,共3页
Journal of Bengbu Medical College
关键词
气体中毒
光气
临床特点
gas poisoning
phosgene
clinical features
