摘要
1例60岁男性胃癌晚期患者,给予多西他赛联合顺铂、氟尿嘧啶化疗,第6天开始出现骨髓抑制,第9天达到高峰,白细胞降至0.73×109.L-1,血小板最低39×109.L-1;同时合并高热及重度低钾血症,血钾最低1.98 mmol.L-1。给予皮下注射重组人粒细胞集落刺激因子、氯化钾注射液持续静脉泵入、预防感染及退热对症处理,患者第12天体温恢复正常,第15天白细胞、血小板及血钾恢复正常。患者安全度过危险期,顺利出院。
One case of 60-year-old male patient with advanced gastric cancer, was treated with docetaxel cisplatin and fluorouracil chemotherapy, bone marrow suppression emerged on the sixth day, and peaked on day 9. WBC counts decreased to 0.73 × 10^9.L^-1, platelet minimum decreased to 39 x 109.L^-1, combined with hyperpyrexia and severe hypokalemia and potassium minimum decreased to 1.98 mmol.L^-1. After subcutaneous injection of subcutaneously recombinant human granulocyte colony stimulating factor and potassium chloride injection pump continuously into veins and prophylactic measurements of infection and abatement of fever, his temperature returned to normal on day 12, WBC and platelet count returned to normal on day 15. The patient passed the critical stage successfully, and was discharged.
出处
《中国药物应用与监测》
CAS
2012年第2期123-124,共2页
Chinese Journal of Drug Application and Monitoring
关键词
化疗
骨髓抑制
低钾血症
Chemotherapy
Bone marrow suppression
Hypokalemia
