摘要
目的观察奥曲肽治疗上消化道出血的疗效。方法选取2008年10月—2011年5月我科收治的40例上消化道出血住院患者,随机分为治疗组与对照组,每组各20例。对照组给予奥美拉唑治疗,治疗组在对照组基础上应用奥曲肽治疗,观察两组止血时间、输血量和再输血发生情况,并比较两组疗效。结果治疗组止血时间短于对照组,输血量少于对照组,差异有统计学意义(P<0.05),治疗组总有效率为90.0%,高于对照组的75.0%,差异有统计学意义(P<0.05)。治疗组再出血1例(10.0%),对照组为4例(20.0%),两组比较差异有统计学意义(P<0.05)。结论常规治疗基础上联用奥曲肽治疗急性上消化道出血能缩短止血时间,减少输血量和降低再出血率,应用安全有效。
Objective To observe the effect of octreotide in treatment of gastrointestinal hemorrhage.Methods 40 cases of uppe gastrointestinal bleeding hospitalized patients were choosen during October 2008 and May 2011 in our department were randomly divided into treatment group and control group（20 patients in each）.The control group received Omeprazole treatment,and the treatment group received octreotide based on the control group,bleeding time,transfusion of blood transfusion and re-occurrence were observed,and the clinical efficacy was compared.Results In the treatment group,bleeding time was shorter than that in the control group,blood transfusion was less than the control group,the difference was statistically significant（P0.05）,total effective rate in the treatment group was 90.0%,which was higher than the 75.0% in the control group,and the difference was statistically significant（P0.05）.Rebleeding in the treatment group was 1 case（10.0%）,and in the control group was 4 patients（20.0%）,the difference was statistically significant（P0.05）.Conclusion Combined with conventional therapy based on the treatment of acute upper gastrointestinal bleeding octreotide can reduce the time to stop bleeding and reduce blood volume and lower rebleeding rate,the application is safe and effective.
出处
《临床合理用药杂志》
2012年第12期41-41,43,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
奥曲肽
上消化道出血
治疗结果
Octreotide
Upper gastrointestinal bleeding
Treatment outcome
