摘要
目的:初步探讨中药干预治疗乳腺癌化疗患者便秘的临床疗效。方法:选择本科行TEC方案乳腺癌化疗患者40例,随机分为治疗组和对照组。治疗组化疗前1日予中药口服,每日1剂,7日为1个疗程,连续治疗2个疗程。对照组不服用中药。观察两组排便次数、排便困难程度、第1次排便时间段、腹痛腹胀程度、恶心程度及呕吐程度。结果:治疗组与对照组间主要疗效指标(排便次数、排便困难程度及第1次排便时间段)具有显著性差异,P<0.05;次要疗效指标(腹痛腹胀程度、恶心程度)具有显著性差异,P<0.05;呕吐程度比较无显著性差异,P>0.05,不排除与样本量较小及化疗后胃肠道反应有一定关系。结论:中药干预对乳腺癌患者化疗中便秘具有一定的临床疗效。
Objective:Discuss the clinical effects with Chinese traditional treatment to prevent chemotherapy induced constipation of breast cancer patients.Methods:40 patients of breast cancer with chemotherapy were divided into treated and controlled group randomly.Compared with the patients of controlled group,the other one was carried out with the herbal decoction daily from the day before chemotherapy to the end of two weeks.Then observe the defecation and concomitant symptoms.Results:The times,difficulty and the time quantum of defecation when the patients accept Chinese traditional treatment are obviously different from controlled group(P〈0.05);the level of bellyache,abdominal distension,nausea of treated group are statistically evident(P〈0.05);except the level of vomit(P〉0.05).Conclusion:The Chinese traditional treatment for patients to prevent chemotherapy induced constipation could gain ideal effect.
出处
《辽宁中医药大学学报》
CAS
2012年第5期202-204,共3页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
中药干预
乳腺癌
化疗
便秘
Chinese medicine treatment
breast cancer
chemotherapy
constipation