摘要
目的：分析殷东风教授临床应用含莪术复方中药治疗恶性肿瘤的用药规律及安全性。方法：采用回顾性研究方法,分析门诊处方中莪术与体力状况（ZPS,5分法）、配伍中药等的关系,及不良事件发生情况;统计住院患者用药前后血常规及肝肾功能的变化。结果1：22例门诊病例中,莪术用量6~15g,用量大小与ZPS评分成反比,与体重成正比;ZPS 0~2分者多伍用柴胡龙骨牡蛎汤,ZPS 3分以上者多伍用加味四君子汤。不良事件发生率为5.74%,无明显出血副作用。66例住院患者用药后无明显肝肾功能、血常规异常变化。结论：在合理的用量及配伍前提下,含莪术复方中药治疗恶性肿瘤无明显副作用发生。
Objective：Analysis on the regularity and security of clinical application compound traditional Chinese medicine（TCM）containing Ezhu treating malignant tumor by professor YIN Dong-feng was made.Method：Use retrospective study method to analyze the relationship between Ezhu and physical condition（ZPS,5 point method）,and the compatibility of TCM.And observe the adverse events and make statistics of the changes of routine blood,liver and kidney function before and after using TCM of hospitalized patients.Results：Among the 122 cases of outpatients,the dosage of Ezhu was 6~15g,the dosage is inversely proportional to physical condition（ZPS）,and propotionalto the weight;Those ZPS0-2 points use Chaihu and Longmu a lot,and the dosage of Ezhu was 15g.ZPS3 points or more use flavored Sijunzi decoction a lot.And the total incidence of adverse events was 5.74%,and no significant bleeding side effects.66 cases hospitalized patients have no obvious changes in routine blood,liver and kidney function after using TCM.Conclusion：Reasonable compatibility and dosage in the premise,the compound TCM formula including Ezhu therapy treating malignant tumor shows a low incidence of adverse events.
出处
《辽宁中医药大学学报》
CAS
2012年第5期113-115,共3页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
莪术
抗肿瘤
安全性
Ezhu
resist malignant tumour
security
