摘要
目的了解我院肿瘤手术患者抗菌药物的应用现状,并分析其合理性,进而促进其合理应用。方法回顾我院近两年来肿瘤外科抗菌药物使用情况,分析其用药的不合理性。结果本研究发现肿瘤手术患者不合理用药占48.89%(220/450),治疗性用药与预防性用药合理性评价无显著差异,P>0.05。在治疗性用药中经微生物培养和药敏试验后用药的占8.33%(25/300),经验性用药占91.67%(275/300);手术后用药大于3d占84.0%(378/450)。主要存在有用药疗程长、换药频繁、联合用药不合理搭配及不合理选药等。结论肿瘤手术患者机体自身抵抗力低,且感染因素较复杂,抗菌药物的合理应用很重要。要加强合理应用抗菌药物的监管,提高用药合理性。
Objective To observe the antibacterial application of patients with tumor surgery in our hospital, and analyze its application rationality, and thus to promote its rational use. Methods To analyze the condition of surgical oncology patients and usage of antibacterial in the past two years. Results The results indicate that tumor patients who received irrational drug use after surgery accounted for 48.89% （220/450）. Evaluation on the reasonableness of therapeutic drugs and preventive medicine had no signifi- cant difference, 19〉 0.05. Among the therapeutic use of drugs, those used after bacterial culture and suscep- tibility test accounted for 8.33% （25/300）, and those used dependent on experiences accounted for 91.67% （275/300）. 84.0% patients received medication after surgery for more than 3 days （378 / 450）. The irration- ality of drug use mainly includes long course of treatment with medication, frequent change of medical pre- scription, unreasonable combination of drugs, irrational drug selection and so on. Conclusion Rational use of antibiotics is very important for tumor patients due to low body resistance and easy susceptibility caused by many complex factors. It is important to strengthen the supervision on use of antimicrobial drugs to en- hance rationality usage.
出处
《肿瘤药学》
CAS
2011年第5期467-469,共3页
Anti-Tumor Pharmacy
关键词
肿瘤
外科
抗菌药物
合理用药
Cancer, Surgery
Antibiotics
Rational use of drug
