摘要
目的 探讨精神分裂症神经系统软体征的发生率及其与临床关系。方法 入院时对符合入组标准的精神分裂症患者进行BPRS评分及12项软体征检查。于疗后1月、2月时各进行一次BPRS评分及软体征检查。结果 精神分裂症神经系统软体征发生率为68％;与文化程度、起病急缓、病期长短及分型无关,而家族史阳性及病情较重者(BPRS>50分)神经系统软体征发生率显著增高。软体征出现平均项数,随着治疗及病情改善也显著减少。结论 神经系统软体征的研究揭示精神分裂症可能存在脑器质性病变的基础。
Objective: To study the incidence of neurological soft signs (NSS) in schizophrenia and its relationship with the clinical features. Method: 75 schizophrenic patients met with criteria were examined with BPRS and 12 item neurological soft sign checklist on the day prior to antipsychotic medication and at the end of the first and second month after antipsychotic medication respectively. Results: The incidence of NSS in schizophrenia was 68 per cent. It is not significantly related to educational leval, type of onset. duration of ilness and type of illness, but significantly related to positive family history and severity of illness. Mealwhile, it significantly decreases after antipsychotic medication and improvement of illness. Conclution: By studying NSS in schizophrenia we may presume that schizophrenia have certen impairment in brain.
出处
《上海精神医学》
2000年第1期32-33,共2页
Shanghai Archives of Psychiatry
