摘要
目的探讨无症状高尿酸血症（HUM）患者血清超敏C-反应蛋白（hs—CRP）水平与颈动脉粥样硬化的相关性。方法测定73例男性无症状高尿酸血症（HUM组）和42例男性健康体检者（对照组）的血清hs—CRP水平和颈动脉内膜一中层厚度（IMT）。分析无症状HUM患者血清hs—CRP与颈动脉IMT的相关性。结果HUM组血清hs—CRP水平较对照组增高，颈动脉IMT明显增厚，差异均有统计学意义。血尿酸水平与颈动脉IMT呈正相关，相关系数r为0．381（P〈0．01）。结论无症状HUM患者血清hs-CRP水平升高，血尿酸水平与颈动脉IMT呈正相关。
Objective To study the relationship between level of high sensitivity C reactive protein and carotid arteriosclerosis in hyperuricemia（HUM） without gout symptoms. Methods Blood samples and clinical data were obtained from 73 cases of HUM without gout symptoms, and 42 cases of healthy controls, serum high sensitivity C reactive protein（hs-CRP） and serum uric acid（SUA） were tested. Carotid artery intima-media thickness（IMT） , an indicator of arteriosclerosis, was measured with ultrasound assess- ment in the two groups. The relationship between serum hs-CRP and carotid artery IMT was analyzed. Results The serum level of hs-CRP increased significantly in HUM patients compared with that in con- trois. The SUA level was related with IMT positively （r = 0. 381, P 〈 0. 01 ）. Conclusions The serum hs-CRP level is significantly elevated in patients with HUM and SUA is positively correlated with IMT.
出处
《中国实用医刊》
2012年第9期26-27,共2页
Chinese Journal of Practical Medicine
