摘要
目的:观察白三烯受体拮抗剂孟鲁司特钠治疗儿童感染后咳嗽的临床疗效。方法:我院2010年4月～2011年4月诊治的感染后咳嗽患儿129例,随机分为对照组、布地奈德治疗组和孟鲁司特钠治疗组共三组,分别给予阿奇霉素干混悬剂、阿奇霉素干混悬剂联合布地奈德及阿奇霉素干混悬剂联合孟鲁司特钠治疗,观察三组咳嗽症状评分变化、显效时间及有效率。结果:与对照组比较,孟鲁司特钠和布地奈德可以明显改善感染后咳嗽患儿的咳嗽症状评分、缩短显效时间、提高总有效率(P<0.05),但孟鲁司特钠治疗组和布地奈德治疗组两者间比较差异无统计学意义(P>0.05)。结论:孟鲁司特钠治疗儿童感染后咳嗽疗效明确、依从性好,值得临床推广。
Objective：To observe the curative effects of leukotriene receptor antagonists montelukast sodium on post infectionem cough in children.Methods：Randomly 129 cases of post infectionem cough were allocated into three groups,treated with azithromycin suspension,azithromycin suspension combined with budesonide atomization inhalation,and azithromycin suspension combined with montelukast sodium,respectively.The cough sign score,improvement time and total effective rate were compared between the three groups.Results：Budesonide and montelukast sodium combined with azithromycin therapy could improve the cough sign score,shorten improvement time,and increase total effective rate apparently,as compared to the control group（P0.05）.But there were no differences between the two treatment groups（P0.05）.Conclusions：Montelukast sodium showed a better curative effect on post infectionem cough in children,and had a higher compliance.It should be widely used in clinics.
出处
《儿科药学杂志》
CAS
2012年第4期19-21,共3页
Journal of Pediatric Pharmacy
关键词
感染
咳嗽
孟鲁司特钠
布地奈德
Infection
Cough
Montelukast Sodium
Budesonide
