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静脉滴注赖氨匹林治疗小儿急性热病效果观察 被引量:8

Observation of Fever Removing Effect of Intravenous Infusion of Lysinipinum on in Acute Juvenile Febrile Diseases
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摘要 目的 :探讨赖氨匹林 (来比林 )在小儿急性热病中的退热效果。方法 :选择小儿急性发热性疾病体温>39℃者 6 0例 ,随机分组 ,治疗组 30例 ,选用赖氨匹林静脉滴注对照组 30例 ,用安痛定肌肉注射 ,分别在用药15和 6 0min后观测体温。结果 :治疗组用药 15min后体温开始下降 2 2例 (73 .3 % ) ,对照组 13例 (4 0 .0 % ) ,P <0 .0 1;治疗组用药 6 0min后体温降至正常 2 8例 (93 .3 % ) ,对照组 2 7例 (90 % ) ,P >0 .0 5。结论 :静脉滴注赖氨匹林用于小儿急性热性疾病退热 ,起效明显快于安痛定组 ,退热效果好 。 To study the fever removing effect of Lysinipinum on the acute juvenile febrile diseases ,60 children with acute febrile diseases,with temperature higher than 39 ℃ ,were studide.30 cases were given intravenous infusion of Lysiniqinum(treatment group )and the other 30 patients were subjected to intramuscular injection of Antondin(control group).Temperature was observed 15 minutes and 30 minutes after the injection.The results showed that the temperature in treatment group began to fall 15 minutes after the treatment in 22 of the 30 cases (73.3%) while in the control group only 12 of the 30 cases(40%)began to drop 15 minutes afte the injection ( P< 0.01 ).60 minutes after the treatment ,the temperature in treatment group fell to normal in 28 of the 30 cases ( 93.3% )and in control group, the temperature was reduced to the normal in 27 of 30 cases(90%, P> 0.05 ).The intravenous infusion of Lysinipinum was better than intramuscular injection of Antondin in terms of fever removing effect .Intravenous infusion of Lysinipinum also was also better than the intramuscular injection of Antondin in that the former was safe and had less side effects.
出处 《药物流行病学杂志》 CAS 2000年第2期63-64,共2页 Chinese Journal of Pharmacoepidemiology
关键词 赖氨匹林 急性热病 退热效果 儿童 治疗 Lysinipinum Acute juvenile febrile diseases Fever removing effect
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参考文献2

  • 11,陈新谦,金有豫,主编.新编药物学.第13版.北京:人民卫生出版社,1993.158
  • 22,王秀怀,倪桂臣,李棠,等.来比林退热疗效观察.临床试验论文集,1995.10 (1999-12-09收稿2000-02-21修回)

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