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依那普利与左旋氨氯地平联合治疗原发性高血压合并2型糖尿病微量蛋白尿的观察 被引量:8

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摘要 目的观察依那普利和左旋氨氯地平(施慧达)对原发性高血压合并2型糖尿病微量蛋白尿的影响。方法将117例原发性高血压合并2型糖尿病微量蛋白尿患者随机分为依那普利组(38例)、左旋氨氯地平组(39例)、依那普利+左旋氨氯地平组(40例),服药3个月后,观察用药前后的血压水平及尿微量白蛋白的变化。结果 3组降压效果均明显,依那普利+左旋氨氯地平用药组尤其显著(P<0.05);尿微量白蛋白排泄率均有所下降,且依那普利+左旋氨氯地平组下降更明显(P<0.05)。结论依那普利、左旋氨氯地平均可有效降低血压,且依那普利联合左旋氨氯地平可显著降低微量蛋白尿,具有显著的肾功能保护作用。
出处 《河北医科大学学报》 CAS 2012年第2期183-185,共3页 Journal of Hebei Medical University
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