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地佐辛硬膜外与静脉注射给药预防阑尾牵拉反应的效果比较 被引量:3

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摘要 目的观察并比较地佐辛硬膜外与静脉注射两种给药途径预防阑尾牵拉反应的效果。方法选择美国麻醉医师协会(ASA)分级Ⅰ~Ⅱ级、在硬膜外麻醉下行阑尾切除术患者60例,随机均分为硬膜外注射组和静脉注射组。切皮前分别经硬膜外和静脉注射2.5 mg地佐辛,观察术中患者对牵拉阑尾的反应情况。结果两种注射途径均有预防牵拉反应的效果,但硬膜外注射组优良率高于静脉注射组(P<0.05);两组患者注射给药后脉搏氧饱和度及平均动脉压差异无统计学意义(P>0.05),硬膜外注射组不良反应较静脉注射组少。结论地佐辛硬膜外和静脉注射均有预防阑尾牵拉反应的效果,但硬膜外注射更安全、有效。
作者 刘冬炎
出处 《中国药业》 CAS 2012年第7期73-74,共2页 China Pharmaceuticals
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