摘要
目的评价甲壳素粉状敷料对皮肤浅部切割伤的止痛作用及临床应用的安全性。方法将60例浅部切割伤病人随机分为两组,敷用云南白药组(对照组)30例,敷用甲壳素粉状敷料组(实验组)30例,临床观察7 d并评价其临床效果及安全性。结果实验组止痛疗效总有效率为96.66%,对照组100%,两组比较无统计学意义(P>0.05);实验组疼痛起效时间有效率为80%,对照组96.66%(P>0.05);另外,两组间红肿消失率、渗液消失率、伤口愈合率、化脓性感染发生率比较无显著差异(P>0.05)。无不良事件发生。结论甲壳素粉状敷料具有良好的止痛效果,且临床应用安全。
Objective To investigate the analgesic effect of chitin mealiness excipient on skin superficial cut and its clinical application safety.Methods Sixty patients were divided into control group（treated with Yunnan Baiyao）（n=30） and treatment group（treated with chitin mealiness excipient）（n=30）,then the clinical effect and safety were evaluated after 7 d observation.Results The total effective rates of analgesic efficacy in the treatment group and control group were 96.66% and 100%,respectively.There was no statistical significance between the two groups（P〉0.05）;and the effective rates of initial time for analgesic function in the treatment and control groups were 80% and 96.66%,respectively（P〉0.05）.In addition,the disappearance of swelling,effusion,healing,and the incidence of purulent infection between the two groups showed no significant difference（P〉0.05）.No adverse reaction occurred.Conclusion Chitin mealiness excipient has better analgesic efficacy,and it is safe in clinical application.
出处
《现代药物与临床》
CAS
2012年第2期120-122,共3页
Drugs & Clinic
关键词
甲壳素
临床试验
敷料止痛
起效时间
chitin
clinical trial
excipient
analgesic
initial time of efficacy
