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肠系膜下动脉及卵巢动脉在晚期卵巢癌介入治疗中的价值

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摘要 目的探讨肠系膜下动脉及卵巢动脉在晚期卵巢癌介入治疗中的价值。方法对18例晚期卵巢癌患者在行常规双侧髂内动脉和(或)子宫动脉化疗和(或)栓塞后,对肠系膜下动脉、卵巢动脉参与肿瘤供血者进行灌注化疗和(或)栓塞治疗,3周后腹部CT扫描判断其疗效。结果15例患者肠系膜下动脉参与肿瘤供血,10例患者卵巢动脉参与肿瘤供血,灌注化疗和(或)栓塞治疗后,随访CT见肿块皆有不同程度缩小,腹腔积液明显减少。肠系膜下动脉参与肿瘤血供在FIGODI和Ⅳ期中分别为50.0%(3/6)和100.0%(12/12),两组间差异有统计学意义(P=0.009);卵巢动脉参与肿瘤血供在Ⅲ期中占50.0%(3/6),Ⅳ期中占58.3%(7/12),差异无统计学意义(P=0.165)。结论常规行双侧髂内动脉和(或)子宫动脉化疗灌注和(或)栓塞治疗疗效欠佳的晚期卵巢癌患者,特别是FIGOIV期患者,积极探寻肠系膜下动脉及卵巢动脉并行化疗灌注和(或)栓塞治疗,具有一定的临床价值。
出处 《肿瘤研究与临床》 CAS 2012年第3期203-204,215,共3页 Cancer Research and Clinic
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