摘要
目的:探讨超选择性子宫动脉化疗栓塞在宫颈癌治疗中的疗效及应用价值。方法:选择宫颈癌Ⅰb～Ⅱb期患者56例在超选择性子宫动脉化疗栓塞后行腹腔镜下广泛子宫切除及盆腔淋巴结清扫术作为动脉化疗组,同期Ⅰb～Ⅱa期未行介入化疗直接手术的42例作为对照组,对两组的临床资料进行回顾性分析。结果:动脉化疗组化疗后肿瘤直径较化疗前明显缩小,总有效率89.3%;动脉化疗组手术时间、术中失血量、淋巴结转移及宫旁浸润率均低于对照组,差异有统计学意义(P<0.05);术后膀胱功能、胃肠功能恢复时间及术后并发症发生差异无统计学意义(P>0.05)。结论:术前介入动脉化疗栓塞能明显缩小肿瘤直径,提高手术切除率,减少术中出血,缩短手术时间,不影响术后恢复,不增加术后并发症,是宫颈癌治疗的有效辅助治疗手段。
Objective： To explore the therapeutic efficacy and application value of super - selective uterine artery embolization in the treatment of cervical cancer. Methods： 56 patients with Ⅰ b - Ⅱb period of cervical cancers treated with super selective uterine arte- rial chemotherapy embolism before laparosc0pic hysterectomy and extensive pelvic lymph node dissections were selected into arterial chemo- therapy group, 42 cases with Ⅰ b - Ⅱ a period without intervention chemotherapy while with direct operation were into con＇ttol grotip. Clin- ical data were retrospectively analyzed. Results： Tumor diameter was reduced after chemotherapy in arterial chemotherapy group significant- ly, the total effective rate was 89.3%. Operation time, intraoperative blood loss, lymph node metastasis and palace side infiltration rate in ar- terial chemotherapy group were lower than those of control group, the differences were statistically significant （ P 〈 0. 05 ） . There were no statistical differences in postoperative bladder function, gastrointestinal functional recovery time and postoperative complications between arte- rial chemotherapy and control groups （P 〉 0. 05 ） . Conclusion ： Preoperative intervention arterial chemotherapy embolism could obviously reduce tumor diameter, improve the surgical excision rate, reduce the intraoperative bleeding, shorten the operation time, but not affect postoperative recovery and not increase the postoperative complications, which is effective auxiliary therapy for cervical cancer.
出处
《中国妇幼保健》
CAS
北大核心
2013年第13期2047-2049,共3页
Maternal and Child Health Care of China
关键词
宫颈癌
动脉化疗栓塞
腹腔镜
Cervical cancer
Arterial chemoembolization
Laparoscope
