摘要
目的观察阿卡波糖和二甲双胍治疗IGT患者的效果。方法选择2009年08月～2010年07月门诊和体检中糖耐量受损患者104例,阿卡糖组予阿卡波糖25～100mg,3次/d;或二甲双胍组予盐酸二甲双胍片250～500mg/次,3次/d;疗程1年。结果 2组患者空腹和餐后2h血糖与治疗前比均明显下降,2组药物降低空腹血糖差异无统计学意义,阿卡波糖组控制餐后2h血糖优于二甲双胍组,差异有统计学意义。结论阿卡波糖降低餐后糖优于二甲双胍。
Objective To compare the effectiveness and security of acarbose and metformin in the treatment for impaired glucose tolerance Methods One hundred and four impaired glucose tolerance patients were chosen and were randomly divide them into two groups, 52 cases in the physical examination and outpatient treatment in our hospital from august 2009 to july 2011 each group,acarbose group in which patients were given acarbose tablets of 25~100 mg every time, three times per day, metformin group were given metformin tablets of 250~500 mg every time, three times everyday, treatment for 1 year. Results Fasting plasma glucose and postprandial 2 hour glucose of two groups patients were significantly decreased after they are treated. The drugs of two groups have no significant difference in decreasing fasting blood glucose,which is no statistical significant the Acarbose group in controling postprandial 2h glucose is more efficient than the Metformin group ,which has a statistical significant. Conclusion The Acarbose in decreasing the postprandial blood glucose is better than the Metformin.
出处
《当代医学》
2012年第11期145-146,共2页
Contemporary Medicine
关键词
糖耐量受损
阿卡波糖
二甲双胍
Impaired glucose tolerance
Acarbose
Metformin
