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^(13)C-辛酸呼气试验测定肝硬化胃固体排空功能研究 被引量:7

Measurement of solid gastric emptying by ^(13)C-octanoic acid breath test in patients with cirrhosis
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摘要 目的:观察13C-辛酸呼气试验测定肝硬化患者胃固体排空功能变化特点。方法:选取43例乙肝肝硬化患者测定胃固体食物排空时间并与10例健康对照者的胃固体食物排空时间进行比较,按Child-pugh分级进行A、B、C 3级之间胃固体排空时间的比较。结果:乙肝肝硬化患者GET1/2和Tlag较健康对照组明显延长(P<0.05);乙肝肝硬化组Child-pugh分级A级与健康对照组GET1/2无统计学差异(P>0.05),B级、C级患者GET1/2较健康对照组明显延长(P<0.05)。结论:肝硬化患者存在胃排空延迟,表现为肝功能Child-pugh评分越高胃排空能力越弱;肝硬化患者Child-pugh A级患者与健康正常者比较胃排空无明显延迟。 Objective: To observe the changes of gastric emptying functions in patients with cirrhosis with 13 C-octanoic acid breath test.Methods: Select 43 cases of hepatitis B virus(HBV) related liver cirrhosis and 10 healthy controls.The gastric emptying time of solid food was then measured in both groups and the gastric half-emptying time was compared.Results: The GET 1/2 and Tlag of HBV related liver cirrhosis were prolonged significantly than those of healthy control group(P0.05).There was no significant difference in GET 1/2 of Child-pugh grade A of HBV related cirrhosis and the control group(P0.05).Compared with control group,the GET 1/2 of Child-pugh grade B and C was prolonged significantly(P0.05).Conclusion: There is delayed gastric emptying in patients with cirrhosis,which displays the higher of Child-pugh scores,the weaker of gastric emptying ability.There are not delayed significantly in gastric emptying time in Child-pugh class A patients of HBV related cirrhosis compared with control group.
出处 《天津医科大学学报》 2012年第1期86-88,共3页 Journal of Tianjin Medical University
关键词 13C-辛酸呼气试验 胃半排空时间 肝硬化 胃肠动力 13 C-octanoic acid breath test gastric half-emptying time cirrhosis gastric motility
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参考文献11

  • 1王旭霞,王景杰,赵曙光,秦明,杨琦,雷巧玲,张少玲.肝硬化患者胃电图的变化及胃电起搏对其的治疗作用[J].肝胆外科杂志,2005,13(6):439-441. 被引量:14
  • 2Chitkara D K,Camilleri M,Zinsmeister A R. Gastric sensory and motor dysfunc-tion in adolescents with functional dyspepsia[J].Pediatrics,2005,(04):500.doi:10.1016/j.jpeds.2004.11.031.
  • 3Bromer M Q,Kantor S B,Wagner D A. Simultaneous measurement of gastric emptying with a simple muffin meal using[13C]octanoate breath test and scin tigra-phy in normal subjects and patients with dyspeptic symptoms[J].Digestive Diseases and Sciences,2002,(07):1657.doi:10.1023/A:1015856211261.
  • 4Sanaka M,Yamamoto T,Kuyama Y. Retention,fixation,and loss of the[13C]label:a review for the understandin of gastric emptying breath tests[J].Digestive Diseases and Sciences,2008,(07):1747.doi:10.1007/s10620-007-0103-z.
  • 5Candelli M,Armuzzi A. Gender affects 13C-ketoisocaproic acid breath test[J].European Review for Medical and Pharmacological Sciences,2007,(06):401.
  • 6Inamori M,lida H,Endo H. Aperitif effectson gastric emptying:A crossover study using continuous real-time 13C breath test (breath ID system)[J].Digestive Diseases and Sciences,2009,(04):816.doi:10.1007/s10620-008-0427-3.
  • 7袁爱梅;顾晓江;李力.肝硬化患者胃排空的核素法研究[J]中华医学研究杂志,2005(03):214.
  • 8张瑾,王俊平.^13C-辛酸呼气试验对肝硬化患者胃排空功能的评价[J].中国药物与临床,2008,8(4):315-316. 被引量:8
  • 9唐飞,吕洪敏,向慧玲.肝硬化大鼠胃肠动力与Cajal间质细胞关系的研究[J].天津医科大学学报,2008,14(4):498-500. 被引量:9
  • 10Kalaitzakis E,Sadik R,Holst J J. Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosis[J].Clinical Gastroenterology and Hepatology,2009,(03):346.doi:10.1016/j.cgh.2008.11.022.

二级参考文献16

  • 1陈仕珠,张忠兵,王效民,刘金燕,程秀兰,张洪博,胡家露.肝硬化患者胃、十二指肠粘膜六种胃肠激素含量变化及其临床意义[J].中华消化杂志,1994,14(2):74-77. 被引量:31
  • 2孙斌,牛培勤,申振宇,黄培新,郭传勇,吕中伟.血清胃肠激素在肝硬化患者中的变化及其临床意义[J].同济大学学报(医学版),2005,26(4):38-41. 被引量:10
  • 3朱金照,许其增,刘庆宏.肝硬化大鼠胃窦Cajal间质细胞的变化[J].胃肠病学和肝病学杂志,2005,14(6):618-620. 被引量:18
  • 4李毅,齐清会.胃肠道神经-Cajal间质细胞-平滑肌网络研究进展[J].国际消化病杂志,2007,27(3):225-227. 被引量:11
  • 5Daniel EE. Communication between interstitial cells of Cajal and gastrointestinal muscle[J]. Neurogastroenterol Motil, 2004, 16( 1 ): 118.
  • 6Christensen J, Rick GA, Lowe LS. Distributions of interstitial cells of Cajal in stomach and colon of cat, dog, ferret, opossum, rat, guinea pig and rabbit[J]. J Auton Nerv Syst, 1992, 37(1):47.
  • 7Forster J, Damjanov I, Lin Z, et al. Absence of the interstitial ceils of Cajal in patients with gastroparesis and correlation with clinical findings[J]. J Gastrointest Surg, 2005, 9(1): 102.
  • 8Lin Z, Forster J, Sarosiek I, et al. Baseline status of interstitial cells of Cajal predicts long-term symptom improvement in gastroparetic patients treated with gastric electrical stimulation[J]. Gastroenterology, 2004, 126(Supp12): A-73.
  • 9Nemeth L, Puri P. Three-dimensional morphology of C-kit-positive cellular network and nitrergic innervation in the human gut[J]. Arch Pathol Lab Med,2001, 125(7):899.
  • 10Ghoos YF, Maes BD, Geypens B J, et al. Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath-test. Gastroenterology, 1993,104(6): 1640-1647.

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